diff --git a/stdlib/unittest/case.pyi b/stdlib/unittest/case.pyi
index 1d1206b7fc36..7c8b77f39b79 100644
--- a/stdlib/unittest/case.pyi
+++ b/stdlib/unittest/case.pyi
@@ -102,8 +102,17 @@ class TestCase:
     def assertFalse(self, expr: Any, msg: Any = None) -> None: ...
     def assertIs(self, expr1: object, expr2: object, msg: Any = None) -> None: ...
     def assertIsNot(self, expr1: object, expr2: object, msg: Any = None) -> None: ...
-    def assertIsNone(self, obj: object, msg: Any = None) -> None: ...
+
+    @overload
+    def assertIsNone(self, obj: None, msg: Any = None) -> None: ...
+    @overload
+    def assertIsNone(self, obj: object, msg: Any = None) -> Never: ...
+
+    @overload
+    def assertIsNotNone(self, obj: None, msg: Any = None) -> Never: ...
+    @overload
     def assertIsNotNone(self, obj: object, msg: Any = None) -> None: ...
+
     def assertIn(self, member: Any, container: Iterable[Any] | Container[Any], msg: Any = None) -> None: ...
     def assertNotIn(self, member: Any, container: Iterable[Any] | Container[Any], msg: Any = None) -> None: ...
     def assertIsInstance(self, obj: object, cls: _ClassInfo, msg: Any = None) -> None: ...